The Function of Red Blood Cells: Erythrocyte Pathobiology
نویسندگان
چکیده
منابع مشابه
The unusual pathobiology of hemoglobin constant spring red blood cells.
Hemoglobin Constant Spring (HbCS) is the most common nondeletional alpha-thalassemic mutation and is an important cause of HbH-like disease in Southeast Asia. HbCS variants have an almost normal mean cell volume (MCV) and the anemia is more severe when compared with other alpha-thalassemic variants. We explored the pathobiology of HbCS red blood cells (RBCs) because the underlying cause(s) of t...
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Abstract Background and Objectives There is a circadian rhythm and diurnal variation in the redox capacity in blood plasma and there is a decrease in antioxidant capacity (TAC) during the RBCs storage in blood banking. So it is possible that donated blood, based on donation time, has a different antioxidant capacity and as a result a different biochemical response during storage. This study at...
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The ternary complex of spectrin, actin, and 4.1R (human erythrocyte protein 4.1) defines the nodes of the erythrocyte membrane skeletal network and is inseparable from membrane stability under mechanical stress. These junctions also contain tropomyosin (TM) and the other actinbinding proteins, adducin, protein 4.9, tropomodulin, and a small proportion of capZ, the functions of which are poorly ...
متن کاملIndicators of erythrocyte damage after microwave warming of packed red blood cells.
BACKGROUND Localized overheating of packed red blood cells (PRBCs) after microwave warming with consequent damage to erythrocytes has been reported. We therefore compared possible cellular markers of erythrocyte damage, as measured by flow cytometry, with laboratory indicators of hemolysis to evaluate the effects of microwave warming on PRBCs. METHODS PRBC samples were warmed to room temperat...
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Background and Aims: Thyroid hormones have an important role in metabolism and regulation of the red blood cells (RBCs). Thyroid dysfunction induces various effects on blood cells such as anemia through reducing the oxygen metabolism. For the first time, we aimed to determine the effects of severity activation of hypothyroidism on RBCs indices in patients with hypothyroidism. Materials and Met...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1982
ISSN: 0021-9746
DOI: 10.1136/jcp.35.1.122-c